Anti-CACNB3 antibody (C-Term) (STJ13100079)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from the c-terminal region of rat CACN conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and shares 90% identity with human sequence.
General Information
| Short Description | Rabbit polyclonal anti-CACNB3 (C-Term) for use in IHC and WB in Rat, Mouse and Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Rat/Mouse/Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1: 500 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20ยฐC for long term storage and refrigerated at 2-8ยฐC for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | CACNB3 |
| Gene ID | 784 |
| Uniprot ID | CACB3_HUMAN |
| Immunogen | A synthetic peptide from the c-terminal region of rat CACN conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and shares 90% identity with human sequence. |
| Immunogen Region | C-Term |
| Specificity | Specific for CACNB3. |
Additional Info
| Function | Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation. Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation. |
| Protein Name | Voltage-Dependent L-Type Calcium Channel Subunit Beta-3Cab3Calcium Channel Voltage-Dependent Subunit Beta 3 |
| Database Links | Reactome: R-HSA-112308Reactome: R-HSA-400042Reactome: R-HSA-419037Reactome: R-HSA-422356Reactome: R-HSA-9856532 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Voltage-Dependent L-Type Calcium Channel Subunit Beta-3 antibodyAnti-Cab3 antibodyAnti-Calcium Channel Voltage-Dependent Subunit Beta 3 antibodyAnti-CACNB3 antibodyAnti-CACNLB3 antibody |
Information sourced from Uniprot.org