| Host: |
Rabbit |
| Applications: |
IHC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Voltage-dependent P/Q-type calcium channel subunit alpha-1A (1401-1450 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC-P 1:50-300IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CACNA1A |
| Gene ID: |
773 |
| Uniprot ID: |
CAC1A_HUMAN |
| Immunogen Region: |
1401-1450 aa |
| Specificity: |
CAC1A Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 1401-1450 |
| Function | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents. P/Q-type calcium channels belong to the 'high-voltage activated' (HVA) group and are specifically blocked by the spider omega-agatoxin-IVA (AC P54282). They are however insensitive to dihydropyridines (DHP). |
| Protein Name | Voltage-Dependent P/Q-Type Calcium Channel Subunit Alpha-1aBrain Calcium Channel IBiCalcium Channel - L Type - Alpha-1 Polypeptide Isoform 4Voltage-Gated Calcium Channel Subunit Alpha Cav2.1 |
| Database Links | Reactome: R-HSA-112308Reactome: R-HSA-422356 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Voltage-Dependent P/Q-Type Calcium Channel Subunit Alpha-1a antibodyAnti-Brain Calcium Channel I antibodyAnti-Bi antibodyAnti-Calcium Channel - L Type - Alpha-1 Polypeptide Isoform 4 antibodyAnti-Voltage-Gated Calcium Channel Subunit Alpha Cav2.1 antibodyAnti-CACNA1A antibodyAnti-CACH4 antibodyAnti-CACN3 antibodyAnti-CACNL1A4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
