Anti-CACNA1A antibody (1401-1450 aa) (STJ192574)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 1401-1450
General Information
| Short Description | Rabbit polyclonal anti-Voltage-dependent P/Q-type calcium channel subunit alpha-1A (1401-1450 aa) for use in IHC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC-P 1:50-300IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CACNA1A |
| Gene ID | 773 |
| Uniprot ID | CAC1A_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 1401-1450 |
| Immunogen Region | 1401-1450 aa |
| Specificity | CAC1A Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents. P/Q-type calcium channels belong to the 'high-voltage activated' (HVA) group and are specifically blocked by the spider omega-agatoxin-IVA (AC P54282). They are however insensitive to dihydropyridines (DHP). |
| Protein Name | Voltage-Dependent P/Q-Type Calcium Channel Subunit Alpha-1aBrain Calcium Channel IBiCalcium Channel - L Type - Alpha-1 Polypeptide Isoform 4Voltage-Gated Calcium Channel Subunit Alpha Cav2.1 |
| Database Links | Reactome: R-HSA-112308Reactome: R-HSA-422356 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Voltage-Dependent P/Q-Type Calcium Channel Subunit Alpha-1a antibodyAnti-Brain Calcium Channel I antibodyAnti-Bi antibodyAnti-Calcium Channel - L Type - Alpha-1 Polypeptide Isoform 4 antibodyAnti-Voltage-Gated Calcium Channel Subunit Alpha Cav2.1 antibodyAnti-CACNA1A antibodyAnti-CACH4 antibodyAnti-CACN3 antibodyAnti-CACNL1A4 antibody |
Information sourced from Uniprot.org