| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Carbonic anhydrase 4 (Internal) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CA4 |
| Gene ID: | 762 |
| Uniprot ID: | CAH4_HUMAN |
| Immunogen Region: | Internal |
| Specificity: | CA IV Polyclonal Antibody detects endogenous levels of CA IV protein. |
| Immunogen: | Synthesized peptide derived from the Internal region of human CA IV. |
| Function | Catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons and thus is essential to maintaining intracellular and extracellular pH. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid. |
| Protein Name | Carbonic Anhydrase 4 Carbonate Dehydratase Iv Carbonic Anhydrase Iv Ca-Iv |
| Database Links | Reactome: R-HSA-1237044 Reactome: R-HSA-1247673 Reactome: R-HSA-1475029 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor |
| Alternative Antibody Names | Anti-Carbonic Anhydrase 4 antibody Anti-Carbonate Dehydratase Iv antibody Anti-Carbonic Anhydrase Iv antibody Anti-Ca-Iv antibody Anti-CA4 antibody |
Information sourced from Uniprot.org