Anti-CA4 antibody (Internal) (STJ96493)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the Internal region of human CA IV.
General Information
| Short Description | Rabbit polyclonal anti-Carbonic anhydrase 4 (Internal) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CA4 |
| Gene ID | 762 |
| Uniprot ID | CAH4_HUMAN |
| Immunogen | Synthesized peptide derived from the Internal region of human CA IV. |
| Immunogen Region | Internal |
| Specificity | CA IV Polyclonal Antibody detects endogenous levels of CA IV protein. |
Additional Info
| Function | Catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons and thus is essential to maintaining intracellular and extracellular pH. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid. |
| Protein Name | Carbonic Anhydrase 4Carbonate Dehydratase IvCarbonic Anhydrase IvCa-Iv |
| Database Links | Reactome: R-HSA-1237044Reactome: R-HSA-1247673Reactome: R-HSA-1475029 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Carbonic Anhydrase 4 antibodyAnti-Carbonate Dehydratase Iv antibodyAnti-Carbonic Anhydrase Iv antibodyAnti-Ca-Iv antibodyAnti-CA4 antibody |
Information sourced from Uniprot.org