Anti-C1orf146 antibody (47-173) (STJ11101495)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal C1orf146 (47-173) antibody for use in WB, IF, ICC and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Spo16 |
| Gene ID | 76421 |
| Uniprot ID | SPO16_MOUSE |
| Immunogen Region | 47-173 |
| Immunogen Sequence | GSIVFSLSGVAFLLMDAKEC MTSAEEIFVTKIEKFINIHQ NSFLVLFAPLHGPEEWSLMF RIHQRFLGSNLRILPVHNTV NALDLMCTIAKTTSKPHIDS ICYRMITTKAYIIEQSPVWR TLQKIKL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 47-173 of mouse C1orf146 (NP_877422.2). |
Additional Info
| Tissue Specificity | Testis (at protein level). |
| Function | Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC) thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells. Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1. Required for the localization of TEX11 and MSH4 to recombination intermediates. |
| Protein Name | Protein Spo16 HomologSynaptonemal Complex Reinforcing Element |
| Database Links | |
| Cellular Localisation | Chromosome |
| Alternative Antibody Names | Anti-Protein Spo16 Homolog antibodyAnti-Synaptonemal Complex Reinforcing Element antibodyAnti-Spo16 antibodyAnti-Scre antibody |
Information sourced from Uniprot.org