| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-C1orf146 (47-173) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Spo16 |
| Gene ID: |
76421 |
| Uniprot ID: |
SPO16_MOUSE |
| Immunogen Region: |
47-173 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 47-173 of mouse C1orf146 (NP_877422.2). |
| Immunogen Sequence: |
GSIVFSLSGVAFLLMDAKEC MTSAEEIFVTKIEKFINIHQ NSFLVLFAPLHGPEEWSLMF RIHQRFLGSNLRILPVHNTV NALDLMCTIAKTTSKPHIDS ICYRMITTKAYIIEQSPVWR TLQKIKL |
| Tissue Specificity | Testis (at protein level). |
| Function | Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC) thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells. Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1. Required for the localization of TEX11 and MSH4 to recombination intermediates. |
| Protein Name | Protein Spo16 HomologSynaptonemal Complex Reinforcing Element |
| Cellular Localisation | Chromosome |
| Alternative Antibody Names | Anti-Protein Spo16 Homolog antibodyAnti-Synaptonemal Complex Reinforcing Element antibodyAnti-Spo16 antibodyAnti-Scre antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
