| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-C17orf70 (652-881) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FAAP100 |
| Gene ID: |
80233 |
| Uniprot ID: |
FP100_HUMAN |
| Immunogen Region: |
652-881 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 652-881 of human C17orf70 (NP_079437.5). |
| Immunogen Sequence: |
CLRFPGLAPPHTRAPSPLGP TRDPVATFLETCREPGSQPA GPASLRAEYLPPSVASIKVS AELLRAALKDGHSGVPLCCA TLQWLLAENAAVDVVRARAL SSIQGVAPDGANVHLIVREV AMTDLCPAGPIQAVEIQVES SSLADICRAHHAVVGRMQTM VTEQATQGSSAPDLRVQYLR QIHANHETLLREVQTLRDRL CTEDEASSCATAQRLLQVYR QLRHPSLILL |
| Function | Plays a role in Fanconi anemia-associated DNA damage response network. Regulates FANCD2 monoubiquitination and the stability of the FA core complex. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. |
| Protein Name | Fanconi Anemia Core Complex-Associated Protein 100Fanconi Anemia-Associated Protein Of 100 Kda |
| Database Links | Reactome: R-HSA-6783310 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Fanconi Anemia Core Complex-Associated Protein 100 antibodyAnti-Fanconi Anemia-Associated Protein Of 100 Kda antibodyAnti-FAAP100 antibodyAnti-C17orf70 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
