Anti-DDX31 antibody (652-851) (STJ118337)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DDX31 (652-851) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DDX31 |
| Gene ID | 64794 |
| Uniprot ID | DDX31_HUMAN |
| Immunogen Region | 652-851 |
| Immunogen Sequence | EIKMEDILCVLTRDDCFKGK RWGAQKSHAVGPQEIRERAT VLQTVFEDYVHSSERRVSWA KKALQSFIQAYATYPRELKH IFHVRSLHLGHVAKSFGLRD APRNLSALTRKKRKAHVKRP DLHKKTQSKHSLAEILRSEY SSGMEADIAKVKKQNAPGEP GGRPLQHSLQPTPCFGRGKT LKWRKTQKGVQRDSKTSQKV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 652-851 of human DDX31 (NP_073616.6). |
Additional Info
| Tissue Specificity | Weakly or undetectably expressed in normal organs. Up-regulated in renal cell carcinoma. |
| Function | May have DNA helicase activity and RNA helicase activity. Probably have ssDNA and RNA dependent ATPase activity. Plays a role in ribosome biogenesis and TP53/p53 regulation through its interaction with NPM1. |
| Protein Name | Atp-Dependent Dna Helicase Ddx31Dead Box Protein 31HelicainProbable Atp-Dependent Rna Helicase Ddx31 |
| Database Links | |
| Cellular Localisation | NucleusNucleolusColocalized With Npm1 In The Nucleoli |
| Alternative Antibody Names | Anti-Atp-Dependent Dna Helicase Ddx31 antibodyAnti-Dead Box Protein 31 antibodyAnti-Helicain antibodyAnti-Probable Atp-Dependent Rna Helicase Ddx31 antibodyAnti-DDX31 antibody |
Information sourced from Uniprot.org