Anti-C17orf70 antibody (652-881) (STJ111323)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal C17orf70 (652-881) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FAAP100 |
| Gene ID | 80233 |
| Uniprot ID | FP100_HUMAN |
| Immunogen Region | 652-881 |
| Immunogen Sequence | CLRFPGLAPPHTRAPSPLGP TRDPVATFLETCREPGSQPA GPASLRAEYLPPSVASIKVS AELLRAALKDGHSGVPLCCA TLQWLLAENAAVDVVRARAL SSIQGVAPDGANVHLIVREV AMTDLCPAGPIQAVEIQVES SSLADICRAHHAVVGRMQTM VTEQATQGSSAPDLRVQYLR QIHANHETLLREVQTLRDRL CTEDEASSCATAQRLLQVYR QLRHPSLILL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 652-881 of human C17orf70 (NP_079437.5). |
Additional Info
| Function | Plays a role in Fanconi anemia-associated DNA damage response network. Regulates FANCD2 monoubiquitination and the stability of the FA core complex. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. |
| Protein Name | Fanconi Anemia Core Complex-Associated Protein 100Fanconi Anemia-Associated Protein Of 100 Kda |
| Database Links | Reactome: R-HSA-6783310Reactome: R-HSA-9833482 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Fanconi Anemia Core Complex-Associated Protein 100 antibodyAnti-Fanconi Anemia-Associated Protein Of 100 Kda antibodyAnti-FAAP100 antibodyAnti-C17orf70 antibody |
Information sourced from Uniprot.org