Anti-NNT antibody (881-1086) (STJ116248)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NNT (881-1086) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NNT |
| Gene ID | 23530 |
| Uniprot ID | NNTM_HUMAN |
| Immunogen Region | 881-1086 |
| Immunogen Sequence | NRSLANVILGGYGTTSTAGG KPMEISGTHTEINLDNAIDM IREANSIIITPGYGLCAAKA QYPIADLVKMLTEQGKKVRF GIHPVAGRMPGQLNVLLAEA GVPYDIVLEMDEINHDFPDT DLVLVIGANDTVNSAAQEDP NSIIAGMPVLEVWKSKQVIV MKRSLGVGYAAVDNPIFYKP NTAMLLGDAKKTCDALQAKV RESYQK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 881-1086 of human NNT (NP_036475.3). |
Additional Info
| Tissue Specificity | Widely expressed with expression most readily detectable in adrenal, heart, kidney, thyroid and adipose tissues. |
| Function | The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland. |
| Protein Name | Nad(P Transhydrogenase - MitochondrialNicotinamide Nucleotide TranshydrogenasePyridine Nucleotide Transhydrogenase |
| Database Links | Reactome: R-HSA-71403 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Nad(P Transhydrogenase - Mitochondrial antibodyAnti-Nicotinamide Nucleotide Transhydrogenase antibodyAnti-Pyridine Nucleotide Transhydrogenase antibodyAnti-NNT antibody |
Information sourced from Uniprot.org