• Immunohistochemistry analysis of C12orf10 in paraffin-embedded mouse testis using C12orf10 Rabbit polyclonal antibody (STJ119341) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of C12orf10 in paraffin-embedded human stomach using C12orf10 Rabbit polyclonal antibody (STJ119341) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of C12orf10 in paraffin-embedded rat testis using C12orf10 Rabbit polyclonal antibody (STJ119341) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.

Anti-C12orf10 antibody (48-376) (STJ119341)

SKU:
STJ119341

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Host: Rabbit
Applications: IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-C12orf10 (48-376) is suitable for use in Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MYG1
Gene ID: 60314
Uniprot ID: MYG1_HUMAN
Immunogen Region: 48-376
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 48-376 of human C12orf10 (NP_067653.3).
Immunogen Sequence: GTHNGTFHCDEALACALLRL LPEYRDAEIVRTRDPEKLAS CDIVVDVGGEYDPRRHRYDH HQRSFTETMSSLSPGKPWQT KLSSAGLIYLHFGHKLLAQL LGTSEEDSMVGTLYDKMYEN FVEEVDAVDNGISQWAEGEP RYALTTTLSARVARLNPTWN HPDQDTEAGFKRAMDLVQEE FLQRLDFYQHSWLPARALVE EALAQRFQVDPSGEIVELAK GACPWKEHLYHLESGLSPP
Tissue Specificity Ubiquitously expressed, with highest levels in testis.
Function 3'-5' RNA exonuclease which cleaves in situ on specific transcripts in both nucleus and mitochondrion. Involved in regulating spatially segregated organellar RNA processing, acts as a coordinator of nucleo-mitochondrial crosstalk. In nucleolus, processes pre-ribosomal RNA involved in ribosome assembly and alters cytoplasmic translation. In mitochondrial matrix, processes 3'-termini of the mito-ribosomal and messenger RNAs and controls translation of mitochondrial proteins (Probable).
Protein Name Myg1 Exonuclease
Cellular Localisation Nucleus
Nucleoplasm
Mitochondrion Matrix
Nucleolus
Alternative Antibody Names Anti-Myg1 Exonuclease antibody
Anti-MYG1 antibody
Anti-C12orf10 antibody

Information sourced from Uniprot.org

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