Anti-C12orf10 antibody (48-376) (STJ119341)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal C12orf10 (48-376) antibody for use in IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYG1 |
| Gene ID | 60314 |
| Uniprot ID | MYG1_HUMAN |
| Immunogen Region | 48-376 |
| Immunogen Sequence | GTHNGTFHCDEALACALLRL LPEYRDAEIVRTRDPEKLAS CDIVVDVGGEYDPRRHRYDH HQRSFTETMSSLSPGKPWQT KLSSAGLIYLHFGHKLLAQL LGTSEEDSMVGTLYDKMYEN FVEEVDAVDNGISQWAEGEP RYALTTTLSARVARLNPTWN HPDQDTEAGFKRAMDLVQEE FLQRLDFYQHSWLPARALVE EALAQRFQVDPSGEIVELAK GACPWKEHLYHLESGLSPP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 48-376 of human C12orf10 (NP_067653.3). |
Additional Info
| Tissue Specificity | Ubiquitously expressed, with highest levels in testis. |
| Function | 3'-5' RNA exonuclease which cleaves in situ on specific transcripts in both nucleus and mitochondrion. Involved in regulating spatially segregated organellar RNA processing, acts as a coordinator of nucleo-mitochondrial crosstalk. In nucleolus, processes pre-ribosomal RNA involved in ribosome assembly and alters cytoplasmic translation. In mitochondrial matrix, processes 3'-termini of the mito-ribosomal and messenger RNAs and controls translation of mitochondrial proteins (Probable). |
| Protein Name | Myg1 Exonuclease |
| Database Links | |
| Cellular Localisation | NucleusNucleoplasmMitochondrion MatrixNucleolus |
| Alternative Antibody Names | Anti-Myg1 Exonuclease antibodyAnti-MYG1 antibodyAnti-C12orf10 antibody |
Information sourced from Uniprot.org