| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Peregrin (527-577) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
BRPF1 |
| Gene ID: |
7862 |
| Uniprot ID: |
BRPF1_HUMAN |
| Immunogen Region: |
527-577 |
| Specificity: |
This antibody detects endogenous levels of human BRPF1 |
| Immunogen: |
Synthesized peptide derived from human BRPF1 AA range: 527-577 |
| Post Translational Modifications | Acetylated by KAT6A. |
| Function | Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac). Some HAT complexes preferentially mediate histone H3 'Lys-23' (H3K23ac) acetylation. Positively regulates the transcription of RUNX1 and RUNX2. |
| Protein Name | PeregrinBromodomain And Phd Finger-Containing Protein 1Protein Br140 |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-6804758 |
| Cellular Localisation | NucleusChromosomeCytoplasmLocalization To The Nucleus Depends On Kat6aIng5 And Meaf6Localizes To Transcription Start Sites |
| Alternative Antibody Names | Anti-Peregrin antibodyAnti-Bromodomain And Phd Finger-Containing Protein 1 antibodyAnti-Protein Br140 antibodyAnti-BRPF1 antibodyAnti-BR140 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
