Anti-BRPF1 antibody (527-577) (STJA0006316)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human BRPF1 AA range: 527-577
General Information
| Short Description | Rabbit polyclonal anti-Peregrin (527-577) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BRPF1 |
| Gene ID | 7862 |
| Uniprot ID | BRPF1_HUMAN |
| Immunogen | Synthesized peptide derived from human BRPF1 AA range: 527-577 |
| Immunogen Region | 527-577 |
| Specificity | This antibody detects endogenous levels of human BRPF1 |
Additional Info
| Post Translational Modifications | Acetylated by KAT6A. |
| Function | Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac). Some HAT complexes preferentially mediate histone H3 'Lys-23' (H3K23ac) acetylation. Positively regulates the transcription of RUNX1 and RUNX2. |
| Protein Name | PeregrinBromodomain And Phd Finger-Containing Protein 1Protein Br140 |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-6804758 |
| Cellular Localisation | NucleusChromosomeCytoplasmLocalization To The Nucleus Depends On Kat6aIng5 And Meaf6Localizes To Transcription Start Sites |
| Alternative Antibody Names | Anti-Peregrin antibodyAnti-Bromodomain And Phd Finger-Containing Protein 1 antibodyAnti-Protein Br140 antibodyAnti-BRPF1 antibodyAnti-BR140 antibody |
Information sourced from Uniprot.org