Anti-BRPF1 antibody (527-577) (STJA0006316)

SKU:
STJA0006316
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Peregrin (527-577) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BRPF1
Gene ID: 7862
Uniprot ID: BRPF1_HUMAN
Immunogen Region: 527-577
Specificity: This antibody detects endogenous levels of human BRPF1
Immunogen: Synthesized peptide derived from human BRPF1 AA range: 527-577
Post Translational Modifications Acetylated by KAT6A.
Function Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac). Some HAT complexes preferentially mediate histone H3 'Lys-23' (H3K23ac) acetylation. Positively regulates the transcription of RUNX1 and RUNX2.
Protein Name Peregrin
Bromodomain And Phd Finger-Containing Protein 1
Protein Br140
Database Links Reactome: R-HSA-3214847
Reactome: R-HSA-6804758
Cellular Localisation Nucleus
Chromosome
Cytoplasm
Localization To The Nucleus Depends On Kat6a
Ing5 And Meaf6
Localizes To Transcription Start Sites
Alternative Antibody Names Anti-Peregrin antibody
Anti-Bromodomain And Phd Finger-Containing Protein 1 antibody
Anti-Protein Br140 antibody
Anti-BRPF1 antibody
Anti-BR140 antibody

Information sourced from Uniprot.org

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