Anti-BRD9 antibody (274-597) (STJ11105726)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Bromodomain-Containing Protein 9 (274-597) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BRD9 |
| Gene ID | 65980 |
| Uniprot ID | BRD9_HUMAN |
| Immunogen Region | 274-597 |
| Immunogen Sequence | REVISCMFEPEGNACSLTDS TAEEHVLALVEHAADEARDR INRFLPGGKMGYLKRNGDGS LLYSVVNTAEPDADEEETHP VDLSSLSSKLLPGFTTLGFK DERRNKVTFLSSATTALSMQ NNSVFGDLKSDEMELLYSAY GDETGVQCALSLQEFVKDAG SYSKKVVDDLLDQITGGDHS RTLFQLKQRRNVPMKPPDEA KVGDTLGDSSSSVLEFMSMK SYPDVSVDISMLSSLGKVK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 274-597 of human BRD9 (NP_076413.3). |
Additional Info
| Function | Plays a role in chromatin remodeling and regulation of transcription. Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Also orchestrates the RAD51-RAD54 complex formation and thereby plays a role in homologous recombination (HR). |
| Protein Name | Bromodomain-Containing Protein 9Rhabdomyosarcoma Antigen Mu-Rms-40.8 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Bromodomain-Containing Protein 9 antibodyAnti-Rhabdomyosarcoma Antigen Mu-Rms-40.8 antibodyAnti-BRD9 antibodyAnti-UNQ3040 antibodyAnti-PRO9856 antibody |
Information sourced from Uniprot.org