Anti-BLOC1S6 antibody (1-170) (STJ25026)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal BLOC1S6 (1-170) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BLOC1S6 |
| Gene ID | 26258 |
| Uniprot ID | BL1S6_HUMAN |
| Immunogen Region | 1-170 |
| Immunogen Sequence | MSVPGPSSPDGALTRPPYCL EAGEPTPGLSDTSPDEGLIE DLTIEDKAVEQLAEGLLSHY LPDLQRSKQALQELTQNQVV LLDTLEQEISKFKECHSMLD INALFAEAKHYHAKLVNIRK EMLMLHEKTSKLKKRALKLQ QKRQKEELEREQQREKEFER EKQLTARPAK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human BLOC1S6 (NP_036520.1). |
Additional Info
| Tissue Specificity | Widely expressed. |
| Post Translational Modifications | Phosphorylated. |
| Function | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process. |
| Protein Name | Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 6Bloc-1 Subunit 6Pallid Protein HomologPallidinSyntaxin 13-Interacting Protein |
| Database Links | Reactome: R-HSA-432722 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinIt Can Exist As A Soluble Protein As Well As A Peripheral Membrane Protein |
| Alternative Antibody Names | Anti-Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 6 antibodyAnti-Bloc-1 Subunit 6 antibodyAnti-Pallid Protein Homolog antibodyAnti-Pallidin antibodyAnti-Syntaxin 13-Interacting Protein antibodyAnti-BLOC1S6 antibodyAnti-PA antibodyAnti-PLDN antibody |
Information sourced from Uniprot.org