Anti-BLOC1S6 antibody (1-170) (STJ25026)

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STJ25026
€132.60 - €606.60
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Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:200-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:BLOC1S6
Gene ID:26258
Uniprot ID:BL1S6_HUMAN
Immunogen Region:1-170
Immunogen Sequence:MSVPGPSSPDGALTRPPYCL EAGEPTPGLSDTSPDEGLIE DLTIEDKAVEQLAEGLLSHY LPDLQRSKQALQELTQNQVV LLDTLEQEISKFKECHSMLD INALFAEAKHYHAKLVNIRK EMLMLHEKTSKLKKRALKLQ QKRQKEELEREQQREKEFER EKQLTARPAK
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human BLOC1S6 (NP_036520.1).
Tissue Specificity Widely expressed.
Post Translational Modifications Phosphorylated.
Function Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.
Protein Name Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 6
Bloc-1 Subunit 6
Pallid Protein Homolog
Pallidin
Syntaxin 13-Interacting Protein
Database Links Reactome: R-HSA-432722
Cellular Localisation Cytoplasm
Membrane
Peripheral Membrane Protein
It Can Exist As A Soluble Protein As Well As A Peripheral Membrane Protein
Alternative Antibody Names Anti-Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 6 antibody
Anti-Bloc-1 Subunit 6 antibody
Anti-Pallid Protein Homolog antibody
Anti-Pallidin antibody
Anti-Syntaxin 13-Interacting Protein antibody
Anti-BLOC1S6 antibody
Anti-PA antibody
Anti-PLDN antibody

Information sourced from Uniprot.org