• Western blot analysis of extracts from Jurkat, K562 cells, using BAGE5 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-BAG5 antibody (30-110 aa) (STJ96426)

SKU:
STJ96426

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BAG family molecular chaperone regulator 5 (30-110 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BAG5
Gene ID: 9529
Uniprot ID: BAG5_HUMAN
Immunogen Region: 30-110 aa
Specificity: BAGE5 Polyclonal Antibody detects endogenous levels of BAGE5 protein.
Immunogen: Synthesized peptide derived from BAGE5 at the amino acid range 30-110
Function Co-chaperone for HSP/HSP70 proteins. It functions as a nucleotide-exchange factor promoting the release of ADP from HSP70, thereby activating HSP70-mediated protein refolding. Has an essential role in maintaining proteostasis at junctional membrane complexes (JMC), where it may function as a scaffold between the HSPA8 chaperone and JMC proteins enabling correct, HSPA8-dependent JMC protein folding. Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN.
Protein Name Bag Family Molecular Chaperone Regulator 5
Bag-5
Bcl-2-Associated Athanogene 5
Database Links Reactome: R-HSA-3371453
Cellular Localisation In Cardiomyocytes
Localized At Specialized Membrane Contact Sites Between T-Tubules And The Sarcoplasmic Reticulum
Known As Junctional Membrane Complexes
Alternative Antibody Names Anti-Bag Family Molecular Chaperone Regulator 5 antibody
Anti-Bag-5 antibody
Anti-Bcl-2-Associated Athanogene 5 antibody
Anti-BAG5 antibody
Anti-KIAA0873 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance