| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-BAG family molecular chaperone regulator 5 (30-110 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:5000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
BAG5 |
| Gene ID: |
9529 |
| Uniprot ID: |
BAG5_HUMAN |
| Immunogen Region: |
30-110 aa |
| Specificity: |
BAGE5 Polyclonal Antibody detects endogenous levels of BAGE5 protein. |
| Immunogen: |
Synthesized peptide derived from BAGE5 at the amino acid range 30-110 |
| Function | Co-chaperone for HSP/HSP70 proteins. It functions as a nucleotide-exchange factor promoting the release of ADP from HSP70, thereby activating HSP70-mediated protein refolding. Has an essential role in maintaining proteostasis at junctional membrane complexes (JMC), where it may function as a scaffold between the HSPA8 chaperone and JMC proteins enabling correct, HSPA8-dependent JMC protein folding. Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN. |
| Protein Name | Bag Family Molecular Chaperone Regulator 5Bag-5Bcl-2-Associated Athanogene 5 |
| Database Links | Reactome: R-HSA-3371453 |
| Cellular Localisation | In CardiomyocytesLocalized At Specialized Membrane Contact Sites Between T-Tubules And The Sarcoplasmic ReticulumKnown As Junctional Membrane Complexes |
| Alternative Antibody Names | Anti-Bag Family Molecular Chaperone Regulator 5 antibodyAnti-Bag-5 antibodyAnti-Bcl-2-Associated Athanogene 5 antibodyAnti-BAG5 antibodyAnti-KIAA0873 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
