Anti-B4GAT1 antibody (13-63 aa) (STJ197815)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human B3GN1 at the amino acid range 13-63
General Information
| Short Description | Rabbit polyclonal anti-Beta-1, 4-glucuronyltransferase 1 (13-63 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | B4GAT1 |
| Gene ID | 11041 |
| Uniprot ID | B4GA1_HUMAN |
| Immunogen | Synthesized peptide derived from the human B3GN1 at the amino acid range 13-63 |
| Immunogen Region | 13-63 aa |
| Specificity | This antibody detects endogenous levels of human B3GN1 |
Additional Info
| Function | Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE1, during synthesis of phosphorylated O-mannosyl glycan. Phosphorylated O-mannosyl glycan is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Required for axon guidance.via its function in O-mannosylation of alpha-dystroglycan (DAG1). |
| Protein Name | Beta-1 -4-Glucuronyltransferase 1I-Beta-1 -3-N-AcetylglucosaminyltransferaseIgntN-Acetyllactosaminide Beta-1 -3-N-AcetylglucosaminyltransferasePoly-N-Acetyllactosamine Extension EnzymeUdp-Glcnac -Betagal Beta-1 -3-N-Acetylglucosaminyltransferase 1 |
| Database Links | Reactome: R-HSA-2022854Reactome: R-HSA-5083627Reactome: R-HSA-5173105 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinLocalizes Near The Trans-Golgi Apparatus |
| Alternative Antibody Names | Anti-Beta-1 -4-Glucuronyltransferase 1 antibodyAnti-I-Beta-1 -3-N-Acetylglucosaminyltransferase antibodyAnti-Ignt antibodyAnti-N-Acetyllactosaminide Beta-1 -3-N-Acetylglucosaminyltransferase antibodyAnti-Poly-N-Acetyllactosamine Extension Enzyme antibodyAnti-Udp-Glcnac -Betagal Beta-1 -3-N-Acetylglucosaminyltransferase 1 antibodyAnti-B4GAT1 antibodyAnti-B3GNT1 antibodyAnti-B3GNT6 antibody |
Information sourced from Uniprot.org