| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Beta-1, 4-glucuronyltransferase 1 (13-63 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
B4GAT1 |
| Gene ID: |
11041 |
| Uniprot ID: |
B4GA1_HUMAN |
| Immunogen Region: |
13-63 aa |
| Specificity: |
This antibody detects endogenous levels of human B3GN1 |
| Immunogen: |
Synthesized peptide derived from the human B3GN1 at the amino acid range 13-63 |
| Function | Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE1, during synthesis of phosphorylated O-mannosyl glycan. Phosphorylated O-mannosyl glycan is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Required for axon guidance.via its function in O-mannosylation of alpha-dystroglycan (DAG1). |
| Protein Name | Beta-1 -4-Glucuronyltransferase 1I-Beta-1 -3-N-AcetylglucosaminyltransferaseIgntN-Acetyllactosaminide Beta-1 -3-N-AcetylglucosaminyltransferasePoly-N-Acetyllactosamine Extension EnzymeUdp-Glcnac -Betagal Beta-1 -3-N-Acetylglucosaminyltransferase 1 |
| Database Links | Reactome: R-HSA-2022854Reactome: R-HSA-5083627Reactome: R-HSA-5173105 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinLocalizes Near The Trans-Golgi Apparatus |
| Alternative Antibody Names | Anti-Beta-1 -4-Glucuronyltransferase 1 antibodyAnti-I-Beta-1 -3-N-Acetylglucosaminyltransferase antibodyAnti-Ignt antibodyAnti-N-Acetyllactosaminide Beta-1 -3-N-Acetylglucosaminyltransferase antibodyAnti-Poly-N-Acetyllactosamine Extension Enzyme antibodyAnti-Udp-Glcnac -Betagal Beta-1 -3-N-Acetylglucosaminyltransferase 1 antibodyAnti-B4GAT1 antibodyAnti-B3GNT1 antibodyAnti-B3GNT6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
