Anti-B3GNT5 antibody (167-217) (STJA0006611)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human B3GN5 AA range: 167-217
General Information
| Short Description | Rabbit polyclonal anti-Lactosylceramide 1, 3-N-acetyl-beta-D-glucosaminyltransferaseCer synthase (167-217) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | B3GNT5 |
| Gene ID | 84002 |
| Uniprot ID | B3GN5_HUMAN |
| Immunogen | Synthesized peptide derived from human B3GN5 AA range: 167-217 |
| Immunogen Region | 167-217 |
| Specificity | This antibody detects endogenous levels of human B3GN5 |
Additional Info
| Function | Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer.paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development. |
| Protein Name | Lactosylceramide 1 -3-N-Acetyl-Beta-D-GlucosaminyltransferaseLactotriaosylceramide SynthaseLc(3cer SynthaseLc3 SynthaseUdp-Glcnac -Beta-Gal Beta-1 -3-N-Acetylglucosaminyltransferase 5Bgnt-5Beta-1 -3-Gn-T5Beta-1 -3-N-Acetylglucosaminyltransferase 5Beta3gn-T5 |
| Database Links | Reactome: R-HSA-913709Reactome: R-HSA-9840309 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Lactosylceramide 1 -3-N-Acetyl-Beta-D-Glucosaminyltransferase antibodyAnti-Lactotriaosylceramide Synthase antibodyAnti-Lc(3cer Synthase antibodyAnti-Lc3 Synthase antibodyAnti-Udp-Glcnac -Beta-Gal Beta-1 -3-N-Acetylglucosaminyltransferase 5 antibodyAnti-Bgnt-5 antibodyAnti-Beta-1 -3-Gn-T5 antibodyAnti-Beta-1 -3-N-Acetylglucosaminyltransferase 5 antibodyAnti-Beta3gn-T5 antibodyAnti-B3GNT5 antibody |
Information sourced from Uniprot.org