Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Lactosylceramide 1, 3-N-acetyl-beta-D-glucosaminyltransferaseCer synthase (167-217) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:1000-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
B3GNT5 |
Gene ID: |
84002 |
Uniprot ID: |
B3GN5_HUMAN |
Immunogen Region: |
167-217 |
Specificity: |
This antibody detects endogenous levels of human B3GN5 |
Immunogen: |
Synthesized peptide derived from human B3GN5 AA range: 167-217 |
Function | Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer.paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development. |
Protein Name | Lactosylceramide 1 -3-N-Acetyl-Beta-D-GlucosaminyltransferaseLactotriaosylceramide SynthaseLc(3cer SynthaseLc3 SynthaseUdp-Glcnac -Beta-Gal Beta-1 -3-N-Acetylglucosaminyltransferase 5Bgnt-5Beta-1 -3-Gn-T5Beta-1 -3-N-Acetylglucosaminyltransferase 5Beta3gn-T5 |
Database Links | Reactome: R-HSA-913709 |
Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Antibody Names | Anti-Lactosylceramide 1 -3-N-Acetyl-Beta-D-Glucosaminyltransferase antibodyAnti-Lactotriaosylceramide Synthase antibodyAnti-Lc(3cer Synthase antibodyAnti-Lc3 Synthase antibodyAnti-Udp-Glcnac -Beta-Gal Beta-1 -3-N-Acetylglucosaminyltransferase 5 antibodyAnti-Bgnt-5 antibodyAnti-Beta-1 -3-Gn-T5 antibodyAnti-Beta-1 -3-N-Acetylglucosaminyltransferase 5 antibodyAnti-Beta3gn-T5 antibodyAnti-B3GNT5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance