Anti-B3GALNT2 antibody (STJA0008094)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human B3GALNT2
General Information
| Short Description | Rabbit polyclonal anti-UDP-GalNAc:beta-1, 3-N-acetylgalactosaminyltransferase 2 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | B3GALNT2 |
| Gene ID | 148789 |
| Uniprot ID | B3GL2_HUMAN |
| Immunogen | Synthesized peptide derived from human B3GALNT2 |
| Specificity | This antibody detects endogenous levels of B3GALNT2 at Human, Mouse |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (DAG1) glycosylation: acts coordinately with GTDC2/POMGnT2 to synthesize a GalNAc-beta3-GlcNAc-beta-terminus at the 4-position of protein O-mannose in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan, which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. |
| Protein Name | Udp-Galnac -Beta-1 -3-N-Acetylgalactosaminyltransferase 2Beta-1 -3-Galnac-T2Beta-1 -3-N-Acetylgalactosaminyltransferase Ii |
| Database Links | Reactome: R-HSA-5173105 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Udp-Galnac -Beta-1 -3-N-Acetylgalactosaminyltransferase 2 antibodyAnti-Beta-1 -3-Galnac-T2 antibodyAnti-Beta-1 -3-N-Acetylgalactosaminyltransferase Ii antibodyAnti-B3GALNT2 antibody |
Information sourced from Uniprot.org