| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-UDP-GalNAc:beta-1, 3-N-acetylgalactosaminyltransferase 2 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
B3GALNT2 |
| Gene ID: |
148789 |
| Uniprot ID: |
B3GL2_HUMAN |
| Specificity: |
This antibody detects endogenous levels of B3GALNT2 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human B3GALNT2 |
| Post Translational Modifications | N-glycosylated. |
| Function | Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (DAG1) glycosylation: acts coordinately with GTDC2/POMGnT2 to synthesize a GalNAc-beta3-GlcNAc-beta-terminus at the 4-position of protein O-mannose in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan, which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. |
| Protein Name | Udp-Galnac -Beta-1 -3-N-Acetylgalactosaminyltransferase 2Beta-1 -3-Galnac-T2Beta-1 -3-N-Acetylgalactosaminyltransferase Ii |
| Database Links | Reactome: R-HSA-5173105 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Udp-Galnac -Beta-1 -3-N-Acetylgalactosaminyltransferase 2 antibodyAnti-Beta-1 -3-Galnac-T2 antibodyAnti-Beta-1 -3-N-Acetylgalactosaminyltransferase Ii antibodyAnti-B3GALNT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
