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Polyclonal Antibodies
Anti-B2M antibody (40-120 aa) (STJ192491)

Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-B2M antibody (40-120 aa) (STJ192491)

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STJ192491

€57.50 - €282.50

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Beta-2-microglobulin (40-120 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	B2M
Gene ID:	567
Uniprot ID:	B2MG_HUMAN
Immunogen Region:	40-120 aa
Specificity:	B2MG Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from the human protein at the amino acid range 40-120

Function	Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.
Protein Name	Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3
Database Links	Reactome: R-HSA-1236974 Reactome: R-HSA-1236977 Reactome: R-HSA-164940 Reactome: R-HSA-198933 Reactome: R-HSA-2172127 Reactome: R-HSA-2424491 Reactome: R-HSA-6798695 Reactome: R-HSA-877300 Reactome: R-HSA-9637628 Reactome: R-HSA-9705671 Reactome: R-HSA-977225 Reactome: R-HSA-983170
Cellular Localisation	Secreted Cell Surface Detected In Serum And Urine (Microbial Infection) In The Presence Of M Tuberculosis Esxa-Esxb Complex Decreased Amounts Of B2m Are Found On The Cell Surface
Alternative Antibody Names	Anti-Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3 antibody Anti-B2M antibody Anti-CDABP0092 antibody Anti-HDCMA22P antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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