• Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-B2M antibody (40-120 aa) (STJ192491)

SKU:
STJ192491

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Beta-2-microglobulin (40-120 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: B2M
Gene ID: 567
Uniprot ID: B2MG_HUMAN
Immunogen Region: 40-120 aa
Specificity: B2MG Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 40-120
Function Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.
Protein Name Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3
Database Links Reactome: R-HSA-1236974
Reactome: R-HSA-1236977
Reactome: R-HSA-164940
Reactome: R-HSA-198933
Reactome: R-HSA-2172127
Reactome: R-HSA-2424491
Reactome: R-HSA-6798695
Reactome: R-HSA-877300
Reactome: R-HSA-9637628
Reactome: R-HSA-9705671
Reactome: R-HSA-977225
Reactome: R-HSA-983170
Cellular Localisation Secreted
Cell Surface
Detected In Serum And Urine
(Microbial Infection) In The Presence Of M
Tuberculosis Esxa-Esxb Complex Decreased Amounts Of B2m Are Found On The Cell Surface
Alternative Antibody Names Anti-Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3 antibody
Anti-B2M antibody
Anti-CDABP0092 antibody
Anti-HDCMA22P antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance