Anti-ATP2B4 antibody (1141-1205) (STJ112144)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ATP2B4 (1141-1205) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATP2B4 |
| Gene ID | 493 |
| Uniprot ID | AT2B4_HUMAN |
| Immunogen Region | 1141-1205 |
| Immunogen Sequence | ELPRTPLLDEEEEENPDKAS KFGTRVLLLDGEVTPYANTN NNAVDCNQVQLPQSDSSLQS LETSV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1141-1205 of human ATP2B4 (NP_001675.3). |
Additional Info
| Tissue Specificity | Isoform XB is the most abundant isoform and is expressed ubiquitously. Isoforms containing segment Z have only been detected in heart, while isoforms containing segment a have been found in heart, stomach and brain cortex. |
| Function | Calcium/calmodulin-regulated and magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell. By regulating sperm cell calcium homeostasis, may play a role in sperm motility. |
| Protein Name | Plasma Membrane Calcium-Transporting Atpase 4Pmca4Matrix-Remodeling-Associated Protein 1Plasma Membrane Calcium Atpase Isoform 4Plasma Membrane Calcium Pump Isoform 4 |
| Database Links | Reactome: R-HSA-418359Reactome: R-HSA-5578775Reactome: R-HSA-936837 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionCiliumFlagellum Membrane |
| Alternative Antibody Names | Anti-Plasma Membrane Calcium-Transporting Atpase 4 antibodyAnti-Pmca4 antibodyAnti-Matrix-Remodeling-Associated Protein 1 antibodyAnti-Plasma Membrane Calcium Atpase Isoform 4 antibodyAnti-Plasma Membrane Calcium Pump Isoform 4 antibodyAnti-ATP2B4 antibodyAnti-ATP2B2 antibodyAnti-MXRA1 antibody |
Information sourced from Uniprot.org