| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ATP1A4 (1-90) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ATP1A4 |
| Gene ID: |
480 |
| Uniprot ID: |
AT1A4_HUMAN |
| Immunogen Region: |
1-90 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human ATP1A4 (NP_653300.2). |
| Immunogen Sequence: |
MGLWGKKGTVAPHDQSPRRR PKKGLIKKKMVKREKQKRNM EELKKEVVMDDHKLTLEELS TKYSVDLTKGHSHQRAKEIL TRGGPNTVTP |
| Tissue Specificity | Specifically expressed in testis. Found in very low levels in skeletal muscle. Expressed in mature sperm (at protein level). |
| Function | This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Plays a role in sperm motility. |
| Protein Name | Sodium/Potassium-Transporting Atpase Subunit Alpha-4Na(+/K(+ Atpase Alpha-4 SubunitSodium Pump Subunit Alpha-4 |
| Database Links | Reactome: R-HSA-5578775Reactome: R-HSA-936837Reactome: R-HSA-9679191 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinIn Mature SpermLocated In The Principle Piece Of The Sperm Flagellum |
| Alternative Antibody Names | Anti-Sodium/Potassium-Transporting Atpase Subunit Alpha-4 antibodyAnti-Na(+/K(+ Atpase Alpha-4 Subunit antibodyAnti-Sodium Pump Subunit Alpha-4 antibodyAnti-ATP1A4 antibodyAnti-ATP1AL2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
