Anti-ASXL2 antibody (1200-1275) {Biotin} (STJ506154)

SKU:
STJ506154-100

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Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ASXL2 (1200-1275) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5-1.5 µg/µl
Dilution Range: WB: 1:500-1:5, 000
ELISA: 1:50, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Asxl2
Gene ID: 75302
Uniprot ID: ASXL2_MOUSE
Immunogen Region: 1200-1275
Immunogen: Synthetic peptide taken within amino acid region 1200-1275 on mouse Putative Polycomb group protein ASXL2.
Function Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity.the function seems to involve differential recruitment of acetylated and methylated histone H3.
Protein Name Putative Polycomb Group Protein Asxl2
Additional Sex Combs-Like Protein 2
Database Links Reactome: R-MMU-5689603
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Putative Polycomb Group Protein Asxl2 antibody
Anti-Additional Sex Combs-Like Protein 2 antibody
Anti-Asxl2 antibody
Anti-Kiaa1685 antibody

Information sourced from Uniprot.org

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