| Host: |
Rabbit |
| Applications: |
ELISA/IP/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ASXL2 (1200-1275) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Biotin |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.5-1.5 µg/µl |
| Dilution Range: |
WB: 1:500-1:5, 000ELISA: 1:50, 000IP: 1:200 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Asxl2 |
| Gene ID: |
75302 |
| Uniprot ID: |
ASXL2_MOUSE |
| Immunogen Region: |
1200-1275 |
| Immunogen: |
Synthetic peptide taken within amino acid region 1200-1275 on mouse Putative Polycomb group protein ASXL2. |
| Function | Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity.the function seems to involve differential recruitment of acetylated and methylated histone H3. |
| Protein Name | Putative Polycomb Group Protein Asxl2Additional Sex Combs-Like Protein 2 |
| Database Links | Reactome: R-MMU-5689603 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Putative Polycomb Group Protein Asxl2 antibodyAnti-Additional Sex Combs-Like Protein 2 antibodyAnti-Asxl2 antibodyAnti-Kiaa1685 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
