Anti-ASTN2 antibody (STJA0004338)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFusion protein of human ASTN2
General Information
| Short Description | Rabbit polyclonal anti-Astrotactin-2 for use in IHC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1.38 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | IHC 1:50-1:300 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ASTN2 |
| Gene ID | 23245 |
| Uniprot ID | ASTN2_HUMAN |
| Immunogen | Fusion protein of human ASTN2 |
Additional Info
| Function | Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1. Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref.6). |
| Protein Name | Astrotactin-2 |
| Database Links | |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinPerikaryonCytoplasmCell CortexEarly EndosomeLate EndosomeCytoplasmic VesicleClathrin-Coated VesicleIntegral Membrane Protein Not Detected At The Cell MembraneDetected In Cytoplasmic Vesicles In The Cell CortexClose To The Anterior Pole Of Migrating NeuronsDetected At The Base Of The Leading Process In Migrating Neurons |
| Alternative Antibody Names | Anti-Astrotactin-2 antibodyAnti-ASTN2 antibodyAnti-KIAA0634 antibody |
Information sourced from Uniprot.org