| Host: |
Rabbit |
| Applications: |
IHC/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Astrotactin-2 is suitable for use in Immunohistochemistry and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: |
Antigen affinity purification |
| Concentration: |
1.38 mg/mL |
| Dilution Range: |
IHC 1:50-1:300 |
| Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Function | Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1. Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref.6). |
| Protein Name | Astrotactin-2 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinPerikaryonCytoplasmCell CortexEarly EndosomeLate EndosomeCytoplasmic VesicleClathrin-Coated VesicleIntegral Membrane Protein Not Detected At The Cell MembraneDetected In Cytoplasmic Vesicles In The Cell CortexClose To The Anterior Pole Of Migrating NeuronsDetected At The Base Of The Leading Process In Migrating Neurons |
| Alternative Antibody Names | Anti-Astrotactin-2 antibodyAnti-ASTN2 antibodyAnti-KIAA0634 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
