Host: |
Rabbit |
Applications: |
WB/IHC/ELISA |
Reactivity: |
Human/Mouse |
Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Protein Asteroid Homolog 1 is suitable for use in Western Blot, Immunohistochemistry and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification: |
Antigen affinity purification |
Concentration: |
0.78 mg/mL |
Dilution Range: |
WB 1:500-1:2000, IHC 1:50-1:300 |
Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
Function | Structure-specific DNA endonuclease that specifically cleaves single-stranded DNA and 3' overhang DNA. Contributes to the control of DNA double-strand break repair choice by antagonizing BRCA1-dependent homologous recombination (HR) and promoting non-homologous end-joining (NHEJ). Recruited to the single-stranded DNA ends by SHLD2 and cleaves the 3' exposed DNA ends, therefore inhibiting DNA end resection (necessary for HR) and promoting DNA end protection (necessary for NHEJ). |
Protein Name | Single-Strand Dna Endonuclease Aste1Protein Asteroid Homolog 1 |
Alternative Antibody Names | Anti-Single-Strand Dna Endonuclease Aste1 antibodyAnti-Protein Asteroid Homolog 1 antibodyAnti-ASTE1 antibodyAnti-HT001 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance