Anti-ASMT antibody (1-298) (STJ28612)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ASMT (1-298) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ASMT |
| Gene ID | 438 |
| Uniprot ID | ASMT_HUMAN |
| Immunogen Region | 1-298 |
| Immunogen Sequence | MGSSEDQAYRLLNDYANGFM VSQVLFAACELGVFDLLAEA PGPLDVAAVAAGVRASAHGT ELLLDICVSLKLLKVETRGG KAFYRNTELSSDYLTTVSPT SQCSMLKYMGRTSYRCWGHL ADAVREGRNQYLETFGVPAE ELFTAIYRSEGERLQFMQAL QEVWSVNGRSVLTAFDLSVF PLMCDLGGDFFKDPLPEADL YILARVLHDWADGKCSHLLE RIYHTCKPGGGILVIESLL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-298 of human ASMT (NP_001164510.1). |
Additional Info
| Tissue Specificity | Expressed in the pineal gland (at protein level). In the retina, very low expression is found at the mRNA level, and not at the protein level. |
| Function | Isoform 1: Catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2: Does not show Acetylserotonin O-methyltransferase activity. Isoform 3: Does not show Acetylserotonin O-methyltransferase activity. |
| Protein Name | Acetylserotonin O-MethyltransferaseHydroxyindole O-MethyltransferaseHiomt |
| Database Links | Reactome: R-HSA-209931 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Acetylserotonin O-Methyltransferase antibodyAnti-Hydroxyindole O-Methyltransferase antibodyAnti-Hiomt antibodyAnti-ASMT antibody |
Information sourced from Uniprot.org