| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ASCC1 (1-180) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ASCC1 |
| Gene ID: |
51008 |
| Uniprot ID: |
ASCC1_HUMAN |
| Immunogen Region: |
1-180 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ASCC1 (NP_001185727.1). |
| Immunogen Sequence: |
MEVLRPQLIRIDGRNYRKNP VQEQTYQHEEDEEDFYQGSM ECADEPCDAYEVEQTPQGFR STLRAPSLLYKHIVGKRGDT RKKIEMETKTSISIPKPGQD GEIVITGQHRNGVISARTRI DVLLDTFRRKQPFTHFLAFF LNEVEVQEGFLRFQEEVLAK CSMDHGVDSSIFQNPKKLHL |
| Tissue Specificity | Ubiquitous. |
| Function | Plays a role in DNA damage repair as component of the ASCC complex. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. May also play a role in the development of neuromuscular junction. |
| Protein Name | Activating Signal Cointegrator 1 Complex Subunit 1Asc-1 Complex Subunit P50Trip4 Complex Subunit P50 |
| Database Links | Reactome: R-HSA-112126 |
| Cellular Localisation | NucleusNucleus SpeckleColocalizes With Prpf8 In Nuclear Speckles In The Absence Of Dna Damage |
| Alternative Antibody Names | Anti-Activating Signal Cointegrator 1 Complex Subunit 1 antibodyAnti-Asc-1 Complex Subunit P50 antibodyAnti-Trip4 Complex Subunit P50 antibodyAnti-ASCC1 antibodyAnti-CGI-18 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
