| Host: |
Rabbit |
| Applications: |
WB/IF/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Arrestin domain-containing protein 1 (167-216 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IF 1:100-300ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ARRDC1 |
| Gene ID: |
92714 |
| Uniprot ID: |
ARRD1_HUMAN |
| Immunogen Region: |
167-216 aa |
| Specificity: |
Arrdc1 Polyclonal Antibody detects endogenous levels of Arrdc1 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human ARRD1 at the amino acid range 167-216 |
| Function | Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates. Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles. More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles. By participating in the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway. |
| Protein Name | Arrestin Domain-Containing Protein 1Alpha-Arrestin 1 |
| Cellular Localisation | Cell MembraneAlso Found In Extracellular Vesicles Different From Exosomes |
| Alternative Antibody Names | Anti-Arrestin Domain-Containing Protein 1 antibodyAnti-Alpha-Arrestin 1 antibodyAnti-ARRDC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
