| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARHGEF3 |
| Gene ID: | 50650 |
| Uniprot ID: | ARHG3_HUMAN |
| Immunogen Region: | 287-526 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 287-526 of human ARHGEF3 (NP_062455.1). |
| Immunogen Sequence: | LEEAINIIQGIVAEINTKTG ESECRYYKERLLYLEEGQKD SLIDSSRVLCCHGELKNNRG VKLHVFLFQEVLVITRAVTH NEQLCYQLYRQPIPVKDLLL EDLQDGEVRLGGSLRGAFSN NERIKNFFRVSFKNGSQSQT HSLQANDTFNKQQWLNCIRQ AKETVLCAAGQAGVLDSEGS FLNPTTGSRELQGETKLEQM DQSDSESDCSMDTSEVSLDC ERMEQTDSSCGNSRHGESN |
| Tissue Specificity | Widely expressed. Highest levels are found in adult brain and skeletal muscle. Lower levels are found in heart and kidney. |
| Function | Acts as a guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases. |
| Protein Name | Rho Guanine Nucleotide Exchange Factor 3Exchange Factor Found In Platelets And Leukemic And Neuronal TissuesXpln |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-8980692Reactome: R-HSA-9013026 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Rho Guanine Nucleotide Exchange Factor 3 antibodyAnti-Exchange Factor Found In Platelets And Leukemic And Neuronal Tissues antibodyAnti-Xpln antibodyAnti-ARHGEF3 antibody |
Information sourced from Uniprot.org
