| Short Description : | Rabbit polyclonal ARF4 (1-180) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARF4 |
| Gene ID: | 378 |
| Uniprot ID: | ARF4_HUMAN |
| Immunogen Region: | 1-180 |
| Immunogen Sequence: | MGLTISSLFSRLFGKKQMRI LMVGLDAAGKTTILYKLKLG EIVTTIPTIGFNVETVEYKN ICFTVWDVGGQDRIRPLWKH YFQNTQGLIFVVDSNDRERI QEVADELQKMLLVDELRDAV LLLFANKQDLPNAMAISEMT DKLGLQSLRNRTWYVQATCA TQGTGLYEGLDWLSNELSKR |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ARF4 (NP_001651.1). |
| Function | GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking.may modulate vesicle budding and uncoating within the Golgi apparatus. Part of the ciliary targeting complex containing Rab11, ASAP1, Rabin8/RAB3IP, RAB11FIP3 and ARF4, which direct preciliary vesicle trafficking to mother centriole and ciliogenesis initiation. |
| Protein Name | Adp-Ribosylation Factor 4 |
| Database Links | Reactome: R-HSA-5620916Reactome: R-HSA-6807878Reactome: R-HSA-6811434 |
| Cellular Localisation | Golgi ApparatusMembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Adp-Ribosylation Factor 4 antibodyAnti-ARF4 antibodyAnti-ARF2 antibody |
Information sourced from Uniprot.org
