| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Apoptosis-resistant E3 ubiquitin protein ligase 1 (354-404 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AREL1 |
| Gene ID: |
9870 |
| Uniprot ID: |
AREL1_HUMAN |
| Immunogen Region: |
354-404 aa |
| Specificity: |
This antibody detects endogenous levels of human K0317 |
| Immunogen: |
Synthesized peptide derived from the human K0317 at the amino acid range 354-404 |
| Function | E3 ubiquitin-protein ligase that catalyzes 'Lys-11'- or 'Lys-33'-linked polyubiquitin chains, with some preference for 'Lys-33' linkages. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates SEPTIN4, DIABLO/SMAC and HTRA2 in vitro. Modulates pulmonary inflammation by targeting SOCS2 for ubiquitination and subsequent degradation by the proteasome. |
| Protein Name | Apoptosis-Resistant E3 Ubiquitin Protein Ligase 1Apoptosis-Resistant Hect-Type E3 Ubiquitin Transferase 1 |
| Database Links | Reactome: R-HSA-983168 |
| Alternative Antibody Names | Anti-Apoptosis-Resistant E3 Ubiquitin Protein Ligase 1 antibodyAnti-Apoptosis-Resistant Hect-Type E3 Ubiquitin Transferase 1 antibodyAnti-AREL1 antibodyAnti-KIAA0317 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
