Anti-AQP3 antibody (200-250) {FITC} (STJ500131)

SKU:
STJ500131-100

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Host: Rabbit
Applications: ELISA/ICC/IF/IHC/IP/WB
Reactivity: Bovine/Human/Mouse/Rat/Sheep
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-AQP3 (200-250) is suitable for use in ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: FITC
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.50-0.57 µg/µl
Dilution Range: WB: 1:500
ELISA: 1:10, 000
IP: 1:200
IHC: 1:100
ICC: 1:100
IF: 1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Aqp3
Gene ID: 65133
Uniprot ID: AQP3_RAT
Immunogen Region: 200-250
Immunogen: Synthetic peptide taken within amino acid region 200-250 on rat Aquaporin 3 protein.
Tissue Specificity Detected in kidney medulla and papilla, in collecting duct cells. Detected in colon.
Function Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
Protein Name Aquaporin-3
Aqp-3
31.4 Kda Water Channel Protein
Aquaglyceroporin-3
Database Links Reactome: R-RNO-432040
Reactome: -RNO-432047
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Basolateral Cell Membrane
Alternative Antibody Names Anti-Aquaporin-3 antibody
Anti-Aqp-3 antibody
Anti-31.4 Kda Water Channel Protein antibody
Anti-Aquaglyceroporin-3 antibody
Anti-Aqp3 antibody

Information sourced from Uniprot.org

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