| Host: |
Rabbit |
| Applications: |
ELISA/ICC/IF/IHC/IP/WB |
| Reactivity: |
Bovine/Human/Mouse/Rat/Sheep |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AQP3 (200-250) is suitable for use in ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
FITC |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.50-0.57 µg/µl |
| Dilution Range: |
WB: 1:500ELISA: 1:10, 000IP: 1:200IHC: 1:100ICC: 1:100IF: 1:100 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Aqp3 |
| Gene ID: |
65133 |
| Uniprot ID: |
AQP3_RAT |
| Immunogen Region: |
200-250 |
| Immunogen: |
Synthetic peptide taken within amino acid region 200-250 on rat Aquaporin 3 protein. |
| Tissue Specificity | Detected in kidney medulla and papilla, in collecting duct cells. Detected in colon. |
| Function | Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism. |
| Protein Name | Aquaporin-3Aqp-331.4 Kda Water Channel ProteinAquaglyceroporin-3 |
| Database Links | Reactome: R-RNO-432040Reactome: -RNO-432047 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell Membrane |
| Alternative Antibody Names | Anti-Aquaporin-3 antibodyAnti-Aqp-3 antibodyAnti-31.4 Kda Water Channel Protein antibodyAnti-Aquaglyceroporin-3 antibodyAnti-Aqp3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
