Anti-APOL1 antibody (297-309) (STJ72575)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-APOL1 (297-309) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 42+45kDa bands observed in Human Placenta lysates (calculated MW of 45.9kDa and 42.2kDa according to NP_663318.1 and NP_001130013.1 resp.). Recommended concentration: 0.1-0.3µg/ |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | APOL1 |
| Gene ID | 8542 |
| Uniprot ID | APOL1_HUMAN |
| Accession Number | NP_003652.2; NP_663318.1; NP_001130013.1 |
| Immunogen Region | 297-309 |
| Immunogen Sequence | PHASASRPRVTEP |
| Specificity | This antibody is expected to recognize all three reported isoforms (NP_003652.2; NP_663318.1; NP_001130013.1). Reported variants represent identical protein: NP_003652.2, NP_001130012.1 |
Additional Info
| Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. |
| Function | May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. |
| Protein Name | Apolipoprotein L1Apolipoprotein LApo-LApolApolipoprotein L-IApol-I |
| Database Links | Reactome: R-HSA-2168880Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Apolipoprotein L1 antibodyAnti-Apolipoprotein L antibodyAnti-Apo-L antibodyAnti-Apol antibodyAnti-Apolipoprotein L-I antibodyAnti-Apol-I antibodyAnti-APOL1 antibodyAnti-APOL antibody |
Information sourced from Uniprot.org