Host: |
Goat |
Applications: |
Pep-ELISA/IHC |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-APOC1 (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
IHC-Recommended concentration, 3-5µg/mlELISA-antibody detection limit dilution 1:8000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
APOC1 |
Gene ID: |
341 |
Uniprot ID: |
APOC1_HUMAN |
Immunogen Region: |
C-Term |
Accession Number: |
NP_001636.1 |
Immunogen Sequence: |
ETFQKVKEKLKIDS |
Function | Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein. |
Protein Name | Apolipoprotein C-IApo-CiApoc-IApolipoprotein C1 Cleaved Into - Truncated Apolipoprotein C-I |
Database Links | Reactome: R-HSA-8866423Reactome: R-HSA-8964046Reactome: R-HSA-9029569 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Apolipoprotein C-I antibodyAnti-Apo-Ci antibodyAnti-Apoc-I antibodyAnti-Apolipoprotein C1 Cleaved Into - Truncated Apolipoprotein C-I antibodyAnti-APOC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance