Anti-APOC1 antibody (C-Term) (STJ71162)

SKU:
STJ71162-100

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Host: Goat
Applications: Pep-ELISA/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-APOC1 (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-Recommended concentration, 3-5µg/ml
ELISA-antibody detection limit dilution 1:8000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: APOC1
Gene ID: 341
Uniprot ID: APOC1_HUMAN
Immunogen Region: C-Term
Accession Number: NP_001636.1
Immunogen Sequence: ETFQKVKEKLKIDS
Function Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
Protein Name Apolipoprotein C-I
Apo-Ci
Apoc-I
Apolipoprotein C1 Cleaved Into - Truncated Apolipoprotein C-I
Database Links Reactome: R-HSA-8866423
Reactome: R-HSA-8964046
Reactome: R-HSA-9029569
Cellular Localisation Secreted
Alternative Antibody Names Anti-Apolipoprotein C-I antibody
Anti-Apo-Ci antibody
Anti-Apoc-I antibody
Anti-Apolipoprotein C1 Cleaved Into - Truncated Apolipoprotein C-I antibody
Anti-APOC1 antibody

Information sourced from Uniprot.org

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