| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Mouse/Rat/Dog/Cow/Pig |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-APOA1BP (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.5-1.5µg/mlELISA-antibody detection limit dilution 1:1000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
NAXE |
| Gene ID: |
128240 |
| Uniprot ID: |
NNRE_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_658985.2 |
| Immunogen Sequence: |
PPYPDTECVYRLQ |
| Post Translational Modifications | Undergoes physiological phosphorylation during sperm capacitation, downstream to PKA activation. |
| Function | Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. |
| Protein Name | Nad(Ph-Hydrate EpimeraseApolipoprotein A-I-Binding ProteinAi-BpNad(Phx EpimeraseYjef N-Terminal Domain-Containing Protein 1Yjef_n1 |
| Database Links | Reactome: R-HSA-197264 |
| Cellular Localisation | MitochondrionSecretedIn SpermSecretion Gradually Increases During Capacitation |
| Alternative Antibody Names | Anti-Nad(Ph-Hydrate Epimerase antibodyAnti-Apolipoprotein A-I-Binding Protein antibodyAnti-Ai-Bp antibodyAnti-Nad(Phx Epimerase antibodyAnti-Yjef N-Terminal Domain-Containing Protein 1 antibodyAnti-Yjef_n1 antibodyAnti-NAXE antibodyAnti-AIBP antibodyAnti-APOA1BP antibodyAnti-YJEFN1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
