Anti-APOA1BP antibody (C-Term) (STJ71648)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-APOA1BP (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow/Pig |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:1000.WB: Approx 29kDa band observed in Human Heart lysates (calculated MW of 31.7kDa according to NP_658985.2). Recommended concentration: 0.5-1.5ยตg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | NAXE |
| Gene ID | 128240 |
| Uniprot ID | NNRE_HUMAN |
| Accession Number | NP_658985.2 |
| Immunogen Region | C-Term |
| Immunogen Sequence | PPYPDTECVYRLQ |
Additional Info
| Post Translational Modifications | Undergoes physiological phosphorylation during sperm capacitation, downstream to PKA activation. |
| Function | Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. |
| Protein Name | Nad(Ph-Hydrate EpimeraseApolipoprotein A-I-Binding ProteinAi-BpNad(Phx EpimeraseNaxeYjef N-Terminal Domain-Containing Protein 1Yjef_n1 |
| Database Links | Reactome: R-HSA-197264 |
| Cellular Localisation | MitochondrionSecretedIn SpermSecretion Gradually Increases During Capacitation |
| Alternative Antibody Names | Anti-Nad(Ph-Hydrate Epimerase antibodyAnti-Apolipoprotein A-I-Binding Protein antibodyAnti-Ai-Bp antibodyAnti-Nad(Phx Epimerase antibodyAnti-Naxe antibodyAnti-Yjef N-Terminal Domain-Containing Protein 1 antibodyAnti-Yjef_n1 antibodyAnti-NAXE antibodyAnti-AIBP antibodyAnti-APOA1BP antibodyAnti-YJEFN1 antibody |
Information sourced from Uniprot.org