| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-APCS (1-223) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
APCS |
| Gene ID: |
325 |
| Uniprot ID: |
SAMP_HUMAN |
| Immunogen Region: |
1-223 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-223 of human APCS (NP_001630.1). |
| Immunogen Sequence: |
MNKPLLWISVLTSLLEAFAH TDLSGKVFVFPRESVTDHVN LITPLEKPLQNFTLCFRAYS DLSRAYSLFSYNTQGRDNEL LVYKERVGEYSLYIGRHKVT SKVIEKFPAPVHICVSWESS SGIAEFWINGTPLVKKGLRQ GYFVEAQPKIVLGQEQDSYG GKFDRSQSFVGEIGDLYMWD SVLPPENILSAYQGTPLPAN ILDWQALNYEIRGYVIIKPL VWV |
| Tissue Specificity | Found in serum and urine. |
| Post Translational Modifications | N-glycosylated with a complex biantennary oligosaccharide chain with a sialic acid at the end (disialo-SAP). Monosialo-SAP as well as asioalo-SAP are also detected. |
| Function | Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin. |
| Protein Name | Serum Amyloid P-ComponentSap9.5s Alpha-1-Glycoprotein Cleaved Into - Serum Amyloid P-Component(1-203 |
| Database Links | Reactome: R-HSA-977225 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Serum Amyloid P-Component antibodyAnti-Sap antibodyAnti-9.5s Alpha-1-Glycoprotein Cleaved Into - Serum Amyloid P-Component(1-203 antibodyAnti-APCS antibodyAnti-PTX2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and AK4 knockout (KO) HeLa cells, using [KO Validated] AK4 Rabbit polyclonal antibody (STJ11100730) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89668/358164/STJ11100730_1__42931.1713122467.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and AK4 knockout (KO) HeLa cells, using [KO Validated] AK4 Rabbit polyclonal antibody (STJ11100730) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
